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An HIV-positive person who takes anti-retroviral drugs after diagnosis, rather than when their health declines, can cut the risk of spreading the virus to uninfected partners by 96%, according to a study. coach outlet The United States National Institutes of Health sampled 1,763 couples in which one partner was infected by HIV. It was abandoned four years early as the trial was so successful. The World Health Organization said it was a "crucial development". The study began in 2005 at 13 sites across across Africa, Asia and the Americas. coach factory outlet HIV-positive patients were split into two groups. In one, individuals were immediately given a course of anti-retroviral drugs. The other group only received the treatment when their white blood cell count fell. Both were given counselling on safe sex practices, free condoms and treatment for sexually transmitted infections. Among those immediately starting anti-retroviral therapy there was only one case of transmission between partners. Nike outlet In the other group there were 27 HIV transmissions. 'Renewed commitment' "This breakthrough is a serious game changer and will drive the prevention revolution forward. It makes HIV treatment a new priority prevention option," said Michel Sidibe, executive director of the Joint United Nations Programme on HIV/Aids (UNAIDS). The World Health Organization says sexual transmission accounts for 80% of all new HIV infections. Its director general, Dr Margaret Chan, described the announcement as a "crucial development" cheap coach handbags outlet She added: "The findings from this study will further strengthen and support the new guidance that WHO is releasing in July to help people living with HIV protect their partners." The value of anti-retrovirals, in preventing transmission, had been speculated for some time after observational studies, but researchers say this is the first time it has been proven in clinical trials. Keith Alcorn, from the NAM, an HIV/AIDS charity, said: "This study resoundingly confirms what lots of smaller studies have been telling us for several years. Nike sb shoes "International donors cannot ignore the evidence any longer: HIV treatment is a very powerful form of HIV prevention, and could have a major effect on the HIV epidemic in the worst-affected countries. "What we need now is a renewed commitment to HIV treatment, and studies to show how to get the maximum benefit out of this breakthrough at country level."

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US hedge fund billionaire Raj Rajaratnam has been found guilty of making tens of millions of dollars from insider trading. Nike Dunk SB Low The unanimous verdict, which he plans to appeal, ends an eight-week trial in what prosecutors call the largest hedge fund insider trading case in history. Central to the prosecution's evidence were tapped phone calls between Rajaratnam and corporate insiders. Rajaratnam faces between 15-and-a-half and 19-and-a-half years in jail. 'Greed and corruption' He was released on a $100m (£61m) bail with an electronic tag until the sentencing date of 29 July, although prosecutors had asked for him to be kept in custody, saying he may flee to his native Sri Lanka. Coach Jewelrys Continue reading the main story Rajaratnam was found guilty on all of the 14 charges he faced, including five counts of conspiracy and nine of securities fraud. The hedge fund manager's defence attorney said they would appeal the verdict, noting that 23 of the 37 original accusations against his client had already been dropped before the trial began. The jury decision was postponed for several days after one juror fell ill and had to be replaced, forcing the jury to restart their deliberations from the beginning. Jurors went back to the courtroom repeatedly during their deliberations to listen to sections of the 45 tapes of wire-tapped telephone calls. Nike Dunk SB Mid "Rajaratnam was among the best and the brightest - one of the most educated, successful and privileged professionals in the country," said Manhattan attorney Preet Bharara, who prosecuted the case, in a press release following the verdict. "Yet, like so many others recently, he let greed and corruption cause his undoing." The attorney general's office has charged 47 people with insider trading in the last 18 months, and Rajaratnam is the 35th to be convicted. "The message today is clear - there are rules and there are laws, and they apply to everyone, no matter who you are or how much money you have." Aggressive trading coach outlet Prosecutors argued Rajaratnam made as much as $63.8m (£39m) in illegal profits from 2003 to March 2009 by trading on tips from a network of highly-placed corporate insiders. The companies traded included Google, Intel and Hilton Hotels, the prosecution said. In his final closing arguments, Assistant US Attorney Jonathan Streeter said the Rajaratnam defence team wanted the jury to defy logic and common sense and ignore the evidence provided by dozens of recorded phone calls of illegal trading tips. Prosecutors highlighted conversations they argued showed the win-at-all-cost attitude of Rajaratnam, who wanted to "conquer the market". Coach Backpack Handbags The court heard how investment manager Danielle Chiesi, speaking with Rajaratnam, boasted about one insider tip. "They're going to guide down. I just got a call from my guy - I played him like a fine-tuned piano," she said. In another call, she said she was "glad that we talk on a secure line". Defence attorney John Dowd argued the secretly-recorded conversations were between traders discussing widely-known stock information. He said prosecutors had failed to prove that Rajaratnam had broken any insider-trading laws. Women Nike Dunk SB High The Sri Lankan-born billionaire, 53, is the central figure in a sweeping US government probe of insider trading at hedge funds. More than two dozen people have been criminally or civilly charged in the case. Most of them have pleaded guilty, and Rajaratnam is the first to go to trial. "When that many people pleaded guilty in advance, I'm surprised it went to trial. I'm surprised they didn't try to work out a deal," said Michael Koblenz, a former federal prosecutor. "But if you've got the money and you want to take a shot, maybe it was worth it to him." Coach Sunglasses He suggested that Rajaratnam may have wanted to keep open the option of trying to win the case on appeal.

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Microsoft has confirmed that it has agreed to buy internet phone service Skype. coach outlet The deal will see Microsoft pay $8.5bn (£5.2bn) for Skype, making it Microsoft's largest acquisition. Luxembourg-based Skype has 663 million global users. In August last year it announced plans for a share flotation, but this was subsequently put on hold. Internet auction house eBay bought Skype for $2.6bn in 2006, before selling 70% of it in 2009 for $2bn. This majority stake was bought by a group of investors led by private equity firms Silver Lake and Andreessen Horowit. Other major shareholders include tech-firm Joltid and the Canada Pension Plan Investment Board. Nike outlet Shares in Microsoft ended the day in New York down 0.5% at $25.68. In contrast, eBay - which owns a stake in Skype - saw its share price rally 2.5%. 'Defensive move' Microsoft chief executive Steve Ballmer said: "Skype is a phenomenal service that is loved by millions of people around the world. Microsoft has confirmed that it has agreed to buy internet phone service Skype. The deal will see Microsoft pay $8.5bn (£5.2bn) for Skype, making it Microsoft's largest acquisition. Coach Sunglasses Luxembourg-based Skype has 663 million global users. In August last year it announced plans for a share flotation, but this was subsequently put on hold. Internet auction house eBay bought Skype for $2.6bn in 2006, before selling 70% of it in 2009 for $2bn. This majority stake was bought by a group of investors led by private equity firms Silver Lake and Andreessen Horowit. Other major shareholders include tech-firm Joltid and the Canada Pension Plan Investment Board. Nike sb shoes Shares in Microsoft ended the day in New York down 0.5% at $25.68. In contrast, eBay - which owns a stake in Skype - saw its share price rally 2.5%. 'Defensive move' Microsoft chief executive Steve Ballmer said: "Skype is a phenomenal service that is loved by millions of people around the world. Although the price tag of $8.5bn will not stretch the US giant, some experts have questioned whether it is paying too much for a company that has struggled to turn a profit. Coach Boots Michael Clendenin, managing director of consulting firm RedTech Advisors, said: "If you consider [Skype] was just valued at about $2.5bn 18 months ago when a chunk was sold off, then $8.5bn seems generous. "[It] means Microsoft has a high wall to climb to prove to investors that Skype is a necessary linchpin for the company's online and mobile strategy." This view was echoed by Ben Woods, head of research group CCS Insight. "The big unanswered question is how do Skype assets work for Microsoft... how do you justify the price?" he said. Skype was founded in 2003. nike dunk shoes Calls to other Skype users are free, while the company charges for those made to both traditional landline phones and mobiles.

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The southern US city of Memphis is coping with flood levels not seen since the 1930s, which have forced people from at least 1,300 homes. coach handbags outlet The Mississippi River was expected to crest at 48ft (14.6m) on Monday night in the Tennessee city. The authorities have evacuated low-lying neighbourhoods, but officials said they were confident flood control systems would prevent further harm. The flooding has been caused by melting snow and heavy rains. Army engineers say it is unlikely that the levee system in Memphis will give way, but have admitted that the water has been rising faster than expected Nike outlet The authorities have also warned residents to look out for snakes and rats which could seek shelter on higher ground. Officials downstream in Louisiana have begun evacuating prisoners from one of the state's toughest prisons - the Louisiana State Penitentiary in Angola - and opened floodgates to relieve pressure on levees outside New Orleans. 'Levees holding' The National Weather Service said the Mississippi River would crest later on Monday. The record river height of 48.7ft was set in February 1937 during one of the worst Mississippi floods in US history. Coach Backpack Handbags Officials said they were confident levees along the river would hold back the water and that the authorities had 20,000 sand bags in reserve in case of a breach. Col Vernie Reichling Jr of the Army Corps of Engineers, which manages the Mississippi River flood control system, told reporters: "There should be no concern for any levees to fail." In downtown Memphis, the river had swollen to three miles (4.8km) wide from its typical width of half a mile, the Memphis Commercial Appeal newspaper reported. Further inland, Graceland, the famous home of rock and roll legend Elvis Presley, was out of harm's way, as was Beale Street, a tourist attraction known for Blues music. replica coach outlet "I want to say this: Graceland is safe. And we would charge hell with a water pistol to keep it that way and I'd be willing to lead the charge," director of the Shelby County Emergency Management Agency Bob Nations Jr told the Associated Press. Engorged by the spring thaw, the Mississippi has caused significant flooding upstream in Illinois and Missouri. Further downstream in Arkansas, Mississippi and Louisiana, the river has already passed flood stage.

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An old, frail-looking man sits slouched on a floor, a television remote control in his hand. Kids Dunk Low He strokes his grey beard and rocks gently as he watches himself on the screen. The man is Osama Bin Laden, captured on a tape that the US government says Navy Seals brought back with them from their mission in Abbottabad. The Pentagon describes the results of the raid, during which US soldiers killed the world's most wanted man, as "the largest trove of information ever obtained from a single source". The Pentagon, obviously, has a complete monopoly over the information, and is choosing what it wants the public to see very carefully. cheap coach handbags outlet No audio, no context and no explanation has been provided for the choice of clips that the Pentagon decided to release, nor was there any other information about whether or not they have any further footage. Tarnished image But, by showing a frail and weak Bin Laden, the US is undoubtedly trying to tarnish the image of the al-Qaeda leader in the eyes of his supporters around the world. The five clips released by Pentagon on Saturday prove more that it possesses such material, rather than that it is a source of new information. Nike outlet They show a more familiar Osama Bin Laden sitting against a plain background, speaking straight into the camera, his face lively and animated. It is the same man who often issued video statements both to his enemies and supporters, although in three of the video clips he is rehearsing rather than delivering the actual speeches. Command and control The clips offer no major revelations, but the US government says that other data in their hands proves that, until the day he died, Bin Laden was in charge of al-Qaeda operations and that his compound in Abbottabad was a control-and-command centre for the organisation. coach handbags outlet The Pentagon says that "the largest collection of terrorist material ever" also reveals what US counter-terrorism officials have been trying to establish for years - the role that Osama Bin Laden played in the operations of regional affiliates of his organisation, such as the Yemen-based al-Qaeda in the Arabian Peninsula. Having for years assumed that the organisation operated for the most part independently, Pentagon officials now say that Bin Laden did play a significant role in its activities. If true, his death could be a big blow to a group which sent the so-called "underpants bomber" to blow up a plane over Detroit, and which Washington views as the biggest threat to its homeland security. D&G shoes The Pentagon does not explain details of how, if at all, material gathered in Pakistan will affect the US fight against al-Qaeda elsewhere. While Mr Obama got his man, plenty more remain on the wanted list - including Anwar al-Awlaki, a US-born cleric based in Yemen whom the Pentagon has described as more dangerous than even Bin Laden. On Thursday, less than a week after Bin Laden's death, the US launched a drone strike on a remote area of Yemen in a suspected attempt to kill Mr Awlaki. Sources in Yemen confirm that the attack took place but say that only two low-ranking militants were killed. It is not clear whether the drone attack was linked to information found in Bin Laden's compound but the timing is certainly interesting. replica coach outlet The US drone strike infuriated hundreds of thousands of demonstrators in Yemen, who have been calling for the resignation of Washington's ally in its war on terror - President Ali Abdullah Saleh. Protesters there accuse Mr Saleh of allowing the attack in exchange for support that he desperately needs.

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Nike outlet The US attorney general has said al-Qaeda leader Osama Bin Laden was a lawful military target whose killing was "an act of national self-defence". Eric Holder told a Senate committee that Bin Laden had made no attempt to surrender. The US has acknowledged that Bin Laden was unarmed when shot dead in Monday's raid by US special forces in Pakistan. Meanwhile, the White House has decided not to release photos of the dead Bin Laden. Two couriers and one woman also died in Monday's assault, while one of Bin Laden's wives was injured. Coach Necklaces "If he had surrendered, attempted to surrender, I think we should obviously have accepted that, but there was no indication that he wanted to do that and therefore his killing was appropriate," Mr Holder told the Senate Judiciary Committee. Critics have raised concerns about the legality of the operation. Sightseers Washington has revised its account after initially saying Bin Laden was shot while taking part in a firefight as US Navy Seals stormed the compound. Cheap Nike Dunk High More details have emerged of the information held on 10 computers, 10 mobile phones and 100 USB sticks, yielded by the US raid on the compound where Bin Laden was hiding. Two telephone numbers and 500 Euros ($745; £450) were found stitched into Bin Laden's clothing in case he needed to make a quick getaway, says the BBC's Mark Mardell in Washington. President Barack Obama, who watched the raid from the White House on monitors, saw his approval rating jump 11 points to 57% in a New York Times/CBS News poll on Wednesday. Coach Bracelets He plans to visit the World Trade Center site in New York on Thursday to remember victims of the 11 September attacks, of which Bin Laden was said to have been the mastermind. The Pakistani military has confirmed that it is holding survivors of the US special forces operation. They were being kept at secret locations in the cities of Rawalpindi and Islamabad, said Pakistan army spokesman Maj Gen Athar Abbas. Some of the survivors were being treated for bullet wounds that were serious but not life-threatening, he added Nike Dunk High. The BBC's Aleem Maqbool says the compound where the raid unfolded has now become a sightseers' attraction. There is an ice-cream vendor outside and children selling what they claim is wreckage from a US helicopter, which the Americans said they blew up after it apparently malfunctioned during the operation.

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